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Serenity's Vanguard, sometimes known as simple SV or Vanguard, is a planned Research Class settlement in the Gamma Eratosthenes system in Sector 4 of the Delta Quadrant.

Serenity's Vanguard is controlled by the United Confederation of Systems and is home to the Spacefleet Authority, the agency responsible for defending the UCS and exploring the universe, as well as the native digital based race of Digelans.

In addition to the native Digelans, the system was also initially colonized by Humans and Dzajhan from the Twin States of Eratosthenes and Dzajhema, though members of other races have since immigrated.

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